Homeodomain-interacting protein kinase 2 regulates NLRP3 inflammasome activation through endoplasmic reticulum stress in septic liver injury
Objective Septic liver injury is a major burden for the clinical management of sepsis.Hepatocyte cell death plays a crucial pathophysiological role in sepsis.A recent study proposed that NLRP3 inflammasome-mediated pyroptosis participates in septic liver injury.Therefore, investigating the mechanism controlling this process may help manage sepsis.M