HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 REGULATES NLRP3 INFLAMMASOME ACTIVATION THROUGH ENDOPLASMIC RETICULUM STRESS IN SEPTIC LIVER INJURY

Homeodomain-interacting protein kinase 2 regulates NLRP3 inflammasome activation through endoplasmic reticulum stress in septic liver injury

Objective Septic liver injury is a major burden for the clinical management of sepsis.Hepatocyte cell death plays a crucial pathophysiological role in sepsis.A recent study proposed that NLRP3 inflammasome-mediated pyroptosis participates in septic liver injury.Therefore, investigating the mechanism controlling this process may help manage sepsis.M

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Documenting research with transgender and gender diverse people: protocol for an evidence map and thematic analysis

Abstract Background There is limited information about how transgender, gender diverse, and Two-Spirit (trans) people have been represented and studied by researchers.The objectives of this study are to (1) map and describe trans research in the social sciences, sciences, humanities, health, education, and business, (2) identify evidence gaps and o

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